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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEAF1
All Species:
26.06
Human Site:
S452
Identified Species:
63.7
UniProt:
O75398
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75398
NP_066288.2
565
59327
S452
L
E
L
S
E
P
R
S
W
L
Y
L
E
E
M
Chimpanzee
Pan troglodytes
O77562
565
59322
S452
L
E
L
S
E
P
R
S
W
L
Y
L
E
E
M
Rhesus Macaque
Macaca mulatta
XP_001116691
586
62010
S473
L
E
L
S
E
P
R
S
W
L
Y
L
E
E
M
Dog
Lupus familis
XP_540529
565
59222
S452
L
E
M
S
E
Q
R
S
W
L
Y
L
E
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1T5
566
59614
S453
L
E
M
S
E
H
R
S
W
L
Y
L
E
E
M
Rat
Rattus norvegicus
O88450
565
59513
S452
L
E
M
S
E
H
R
S
W
L
Y
L
E
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001131121
546
58340
S432
L
E
V
T
E
Q
R
S
W
L
Y
L
E
E
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001124251
528
56437
L418
N
V
Q
Q
L
K
V
L
I
A
Q
A
K
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24180
576
61579
R466
K
A
T
N
D
F
K
R
M
L
N
D
M
K
Q
Honey Bee
Apis mellifera
XP_395757
470
51383
R360
K
L
A
Y
E
F
R
R
T
L
E
E
A
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
82.7
93.2
N.A.
93.4
93.8
N.A.
N.A.
82.1
N.A.
47.6
N.A.
24.6
30
N.A.
N.A.
Protein Similarity:
100
99.4
84.6
96.4
N.A.
95.7
96.1
N.A.
N.A.
89
N.A.
62.6
N.A.
40.6
43.3
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
N.A.
80
N.A.
0
N.A.
6.6
20
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
93.3
N.A.
13.3
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
0
0
0
0
10
0
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
70
0
0
80
0
0
0
0
0
10
10
70
70
10
% E
% Phe:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
0
10
10
0
0
0
0
0
10
20
0
% K
% Leu:
70
10
30
0
10
0
0
10
0
90
0
70
0
0
0
% L
% Met:
0
0
30
0
0
0
0
0
10
0
0
0
10
0
70
% M
% Asn:
10
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
20
0
0
0
0
10
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
80
20
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
60
0
0
0
70
0
0
0
0
0
0
0
% S
% Thr:
0
0
10
10
0
0
0
0
10
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
70
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
70
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _